KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROM1
All Species:
17.27
Human Site:
T468
Identified Species:
42.22
UniProt:
O43490
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43490
NP_006008.1
865
97202
T468
C
G
Y
D
R
H
A
T
P
T
T
R
G
C
V
Chimpanzee
Pan troglodytes
XP_517115
865
97216
T468
C
G
Y
D
R
H
A
T
P
T
T
R
G
C
V
Rhesus Macaque
Macaca mulatta
NP_001070888
841
94490
C461
L
G
L
L
C
G
V
C
G
Y
D
R
H
A
T
Dog
Lupus familis
XP_850831
831
93500
Y453
T
L
I
V
V
F
Y
Y
L
G
L
M
C
G
T
Cat
Felis silvestris
Mouse
Mus musculus
O54990
867
97095
T469
F
G
Y
D
K
H
A
T
P
T
R
R
G
C
V
Rat
Rattus norvegicus
Q8CJ52
834
92822
F455
S
L
G
I
W
G
L
F
A
R
E
D
P
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515242
740
82713
S362
L
M
A
G
V
G
F
S
F
L
F
S
W
A
L
Chicken
Gallus gallus
XP_001232165
871
96765
S472
C
G
Y
D
K
H
A
S
P
T
T
R
G
C
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W735
826
91929
T446
C
M
I
V
L
I
L
T
F
N
F
L
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798860
858
93747
S477
F
S
Y
D
R
K
A
S
P
T
D
R
S
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
63.5
N.A.
60.6
26.5
N.A.
44.3
52.8
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
99.4
94.9
80.1
N.A.
78.7
48.3
N.A.
62.3
73.7
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
13.3
0
N.A.
80
0
N.A.
0
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
13.3
0
N.A.
86.6
0
N.A.
13.3
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
50
0
10
0
0
0
0
20
0
% A
% Cys:
40
0
0
0
10
0
0
10
0
0
0
0
10
40
10
% C
% Asp:
0
0
0
50
0
0
0
0
0
0
20
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
20
0
0
0
0
10
10
10
20
0
20
0
0
0
0
% F
% Gly:
0
50
10
10
0
30
0
0
10
10
0
0
50
10
0
% G
% His:
0
0
0
0
0
40
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
20
10
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
20
20
10
10
10
0
20
0
10
10
10
10
0
10
20
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
30
0
0
0
0
10
10
60
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
30
0
0
0
10
10
20
0
% S
% Thr:
10
0
0
0
0
0
0
40
0
50
30
0
0
0
20
% T
% Val:
0
0
0
20
20
0
10
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
50
0
0
0
10
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _